stannous chloride: a reagent for removal of dimethoxytrityl group from 5'-dimethoxytrityl nucleosides
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abstract
detritylation of 5'-dimethoxytrityl nucleosides have been quantitatively achieved in minutes at room temperature under aprotic neutral conditions by using stannous chloride. of additional practical consideration and in contrast to protic acids, no depurination was observed with this reagent.
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Journal title:
iranian journal of chemistry and chemical engineering (ijcce)Publisher: iranian institute of research and development in chemical industries (irdci)-acecr
ISSN 1021-9986
volume 17
issue 2 1998
Keywords
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